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The balance of biogenic amines as condition for normal behaviour

Identifieur interne : 000852 ( Main/Corpus ); précédent : 000851; suivant : 000853

The balance of biogenic amines as condition for normal behaviour

Auteurs : W. Birkmayer ; W. Danielczyk ; E. Neumayer ; P. Riederer

Source :

RBID : ISTEX:F377EC34708C70F8E98E7629BE5B9D6A6312579D

Abstract

Summary: An accumulation of norepinephrin, serotonin and dopamin exists in the brainstem. A decrease of biogenic amines in the brains of Parkinson's cases has been demonstrated. A substitution by the precursor L-DOPA produces an increase of dopamin in the brain and a decrease of serotonin. The high level of dopamin improves the akinesia and the depletion of serotonin causes a toxic delir. A substitution by l-tryptophan restores the balance and the Dopa-psychosis disappears.

Url:
DOI: 10.1007/BF01260902

Links to Exploration step

ISTEX:F377EC34708C70F8E98E7629BE5B9D6A6312579D

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